Heart single cell
Web24 de sept. de 2024 · Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease. Aquí nos gustaría mostrarte una descripción, pero el sitio web que estás mirand… Web10 de jul. de 2024 · Single-cell sequencing on both the healthy and diseased adult heart allows us to study transcriptomic differences between cardiac cells, as well as cell …
Heart single cell
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Web17 de feb. de 2024 · Single-cell sequencing of the heart has provided new insights into cardiomyocyte cycle reentry. Microfluid-based single-cell RNA-seq is not feasible as cardiomyocytes are large and cardiomyocytes have more than one nucleus. Thus, most studies performed single-nucleus sequencing (snRNA-seq) on cardiomyocytes ( 32 ).
WebHace 2 días · Lab Resource: Single Cell Line. Generation of a human induced pluripotent stem cell line from a pediatric heart failure patient with de novo DNM1L mutation. Author links open overlay panel Anshuman Sinha a b, Sameer Guru a b, Shankara Varadarajan a b, Angel Alvarez c, Sunjay Kaushal a b, Xuebin Fu a b. Web7 de jul. de 2024 · During embryonic development, cells differentiate into a variety of distinct cell types and subtypes with diverse transcriptional profiles. To date, transcriptomic signatures of different cell lineages that arise during development have been only partially characterized. Here we used single-cell RNA-seq to perform transcriptomic analysis of …
Web8 de ene. de 2024 · Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function Nature Cell … Web19 de mar. de 2024 · Single-cell RNA-sequencing (scRNA-seq) has been used to study the cellular mechanisms involved in heart development, but does not preserve spatial …
WebHere, we defined >287,000 cCREs in the four chambers of the human heart at single-cell resolution, which revealed cCREs and candidate transcription factors associated with cardiac cell types in a region-dependent manner and during heart failure.
Web29 de ene. de 2024 · Single-cell sequencing reveals dynamic cell type composition during repair of ischemic injury Healing of the heart after ischemic injury is a dynamic process … umms shared servicesWeb19 de nov. de 2024 · Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement Authors Guangshuai Jia # 1 , Jens Preussner # 1 2 , Xi Chen # 3 , Stefan Guenther 1 2 , Xuejun Yuan 1 2 , Michail Yekelchyk 1 2 , Carsten Kuenne 1 2 , Mario Looso 1 2 , Yonggang Zhou 1 , Sarah Teichmann 3 4 5 , Thomas … thorne body shop vicksburg msWebSelected Cell Types . Library Construction Method . Nucleic Acid Source . Paired End . Analysis Protocol . Disease Status (Specimen) Disease Status (Donor) Development Stage . Donor Count . Cell Count Estimate . Submission Date . Update Date . … umms shore medical center chnaWeb12 de feb. de 2024 · The heart is the central organ of the circulatory system, and its proper development is vital for maintaining human life. Here, we used single-cell RNA sequencing to profile the gene expression landscapes of ∼4,000 cardiac cells from human embryos and identified four major types of cells: cardiomyocytes (CMs), cardiac fibroblasts, … umms trainingWeb24 de jul. de 2024 · Nature - Single-cell RNA-sequencing analysis reveals functions of lineage-specifying transcription factors underlying congenital defects in heart development. umms ucmc intranetWebHere we used single-cell RNA sequencing to interrogate early cardiac progenitor cells as they become specified during normal and abnormal cardiogenesis, revealing how … umm study abroadWebAs recent advances in low input RNA-sequencing have allowed definitions of cellular transcriptomes at single cell resolution at scale, here we have applied these approaches to assess the cellular and transcriptional diversity of the non-failing human heart. Methods: Microfluidic encapsulation and barcoding was used to perform single nuclear RNA ... umms srh chestertown