WebBiology questions and answers. A miRNA named lin-4 is important for regulation of development in C. elegans. It regulates the activity of the lin-14 gene, but without causing … WebApr 11, 2024 · The crosstalk and feedback within the heterochronic pathway is remarkable. A recent example of this is the demonstration that lin-4 both directly represses and indirectly promotes lin-28 expression, and that the indirect action is via repression of the let-7 sisters by LIN-14 (another lin-4 target) [63]. Technological advances will certainly ...
F as discussed in class lin 14 and lin 4 are two c - Course Hero
WebJul 15, 2015 · Unlike lin-28, mutations in lin-4 and lin-14 cause L1 cell fates to be skipped or reiterated. At the L4-to-adult transition, seam cells differentiate and secrete a special … Webb. lin-4 encodes a RNA-binding protein and regulates the splicing of lin-14. c. lin-4 encodes a non-coding RNA and inhibits the translation of lin-14 mRNA. d. lin-4 encodes a non-coding RNA and affects the stability of lin-14 mRNA. e. lin-4 encodes a helix-turn-helix motif-containing transcription factor and represses the expression of lin-14. floral print blouse online
The C. elegans heterochronic gene lin-4 encodes small RNAs with ...
WebDec 17, 2024 · In summary, lin-41 regulates two aspects of dauer biology, the decision to enter dauer, and dauer morphogenesis. In both cases, lin-41 appears to act via its canonical target, lin-29.... WebFor example, the heterochronic gene lin-14regulates the timing of synaptic remodeling during larval stage 1 (L1) in the GABAergic Dorsal D (DD) motorneurons (8). LIN-14 also regulates the timing of axon guidance in the AVM, PVM, and PVT neurons (9, 10), and axon degeneration in the PLM neurons (11). WebThe down-regulation of LIN-14 is specified by the action of lin-4. lin-4 encodes a 22-nucleotide regulatory RNA that is thought to act by antisense base-pairing with … great shave soaps